Keep your glassware, apparatus and lab surfaces free of RNase.     

Twice the volume, half the price and at least 4 fold more effective than competitive products Non-carcinogenic

Stable, heat resistant Inactivates >80 µg RNase A Non- alkaline

RNase-OFF® is a non-alkaline cleansing solution that is highly active against RNase contamination. The solution contains a surfactant plus an agent that inactivates RNase. RNase-OFF® has been demonstrated to eliminate >80 µg of RNase A dried onto the bottom of a microcentrifuge tube. This is at least four fold more effective than the leading brand. RNase-OFF® decontamination solution is stable and heat resistant, unlike many alternative products which are not stable and quickly loose their RNase decontamination activity. In addition, RNase-OFF® does not contain carcinogenic compounds.

Effectiveness of RNase-OFF® at removing RNase A.  10 and 80 µg of RNase A were dried onto the bottom of micro-centrifuge tubes. The tubes were treated by adding 1.0ml of RNase decontamination products, vortexing briefly, and rinsing twice with 1.0 ml nuclease free water . Five µg of total RNA (mouse liver) was then added to each tube and incubated for 1 hour at 37°C. The RNA was resolved on a 1.2% agarose gel (1X TAE) and visualized by EtBr staining. Intact rRNA bands (28S and 18S) indicate the absence of RNase contamination.